This represents an exposure of about two and six times the maximum recommended human daily dose of 2000 mg of the metformin component of Glucovance based on body surface online glucovance buy area comparisons for rats and rabbits, respectively. You should let your doctor know if you are going to have any surgery or specialized x-ray procedures that require injection of contrast agents. What does my doctor need to know to decrease my risk of lactic acidosis? Tell your doctor if you have an illness that results in severe vomiting, diarrhea, and or fever, or if your intake of fluids is significantly reduced. GLUCOVANCE was not shown statistically to be superior to either metformin or glyburide with respect to reducing HbA1c from baseline see Table. The doses of metformin and Glucovance were titrated to maximum of four tablets daily as needed to achieve FPG 140 mg dL. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.